Publications

Integration of next-generation sequencing in clinical diagnostic molecular pathology laboratories for analysis of solid tumours; an expert opinion on behalf of IQN Path ASBL

Virchows Arch (2016). doi:

https://doi.org/10.1007/s00428-016-2025-7

Zandra C Deans, Jose Luis Costa, Ian Cree, Els Dequeker, Anders Edsjö, Shirley Henderson, Michael Hummel, Marjolijn JL Ligtenberg, Marco Loddo, Jose Carlos Machado, Antonio Marchetti, Katherine Marquis, Joanne Mason, Nicola Normanno, Etienne Rouleau, Ed Schuuring, Keeda-Marie Snelson, Erik Thunnissen, Bastiaan Tops, Gareth Williams, Han van Krieken, Jacqueline A Hall, On behalf of IQN Path ASBL

Relevance of deep learning to facilitate the diagnosis of HER2 status in breast cancer.

Nature – Scientific Reports, April 2017, 7, 45938 DOI:

https://doi.org/10.1038/srep45938

Michel E. Vandenberghe, Marietta L. J. Scott, Paul W. Scorer et al (2017)

A novel p53-Cdc7 link induced by genotoxic stress

Cell Cycle, DOI:

https://doi.org/10.1080/15384101.2017.1304746

Hisao Masai

Agreement between Programmed Cell Death Ligand-1 Diagnostic Assays across Multiple Protein Expression Cut-Offs in Non-Small Cell Lung Cancer

Clinical Cancer Research, January 2017; 16-2375 DOI:

https://doi.org/10.1158/1078-0432.ccr-16-2375

Marianne J Ratcliffe, Alan Sharpe, Anita Midha et al (2017)

Consistency of tumor and immune cell programmed cell death ligand-1 expression within and between tumor blocks using the VENTANA SP263 assay

Diagnostic Pathology, (2018) 13:47 DOI:

https://doi.org/10.1186/s13000-018-0725-9

Paul Scorer, Marietta Scott, Nicola Lawson et al (2018)

DNA replication licensing factor MCM2, geminin, and Ki67 define proliferative state and are linked with survival in oral squamous cell carcinoma

Eur J Oral Sci. 2018 Jun;126(3):186-196. doi:

https://doi.org/10.1111/eos.12420

Al-Hazmi N, Alhazzazi T, Williams G, Stoeber K, Al-Dabbagh R

Immunophenotypic analysis of cell cycle status in acute myeloid leukaemia: relationship to cytogenetics, genotype and clinical outcome

Br J Haematol. 2018 May;181(4):486-494 [Epub 2018 Apr 20.]

https://doi.org/10.1111/bjh.15211

Sellar RS, Gale RE, Khwaja A, Garbowski M, Loddo M, Stoeber K, Williams GH, Linch DC

Mapping the binding sites of antibodies utilized in programmed cell death ligand-1 predictive immunohistochemical assays for use with immuno-oncology therapies

Mod Pathol. 2019 Sep 26. doi [Epub ahead of print] Erratum in: Mod Pathol. 2019 Oct:

https://doi.org/10.1038/s41379-019-0372-z

Lawson NL, Dix CI, Scorer PW, Stubbs CJ, Wong E, Hutchinson L, McCall EJ, Schimpl M, DeVries E, Walker J, Williams GH, Hunt J, Barker C. (2019)

Assessment of PD-L1 mRNA and protein expression in non-small cell lung cancer, head and neck squamous cell carcinoma and urothelial carcinoma tissue specimens using RNAScope and immunohistochemistry.

PLoS ONE 14(4): e0215393

David Jonathan Duncan ,Marietta Scott,Paul Scorer et al ()

Inter-observer Reliability of Programmed Cell Death Ligand-1 Scoring Using the VENTANA PD-L1 (SP263) Assay in Non-Small Cell Lung Cancer

J Thorac Oncol. 2019 Nov 25. pii: S1556-0864(19)33664-0. doi:

https://doi.org/10.1016/j.jtho.2019.11.010

Williams GH, Nicholson AG, Snead DRJ, Thunnissen E, Lantuejoul S, Cane P, Kerr KM, Loddo M, Scott MLJ, Scorer PW, Barker C. (2019)

Druggable fusion gene landscape in solid tumors

J Clin Oncol 38: 2020 (suppl; abstr e13517) DOI:

https://doi.org/10.1200/JCO.2020.38.15_suppl.e13517

Williams GH, Thatcher RP, Nevado B, Haddow TE, Hardisty KM, Loddo M (2020)

Immunofocus-PD-L1 high throughput quantitative next generation sequencing assay

J Clin Oncol 38: 2020 (suppl; abstr e13521) DOI:

https://doi.org/10.1200/JCO.2020.38.15_suppl.e13521

Williams GH, Thatcher RP, Haddow TE, Hardisty KM, Loddo M (2020)

The actionable genomic mutational landscape in solid tumours

J Clin Oncol 38: 2020 (suppl; abstr e13642) DOI:

https://doi.org/10.1200/JCO.2020.38.15_suppl.e13642

Loddo M, Hardisty KM, Thatcher RP, Haddow TE, Williams GH (2020)

Clinical, Radiometabolic and Immunologic Effects of Olaparib in Locally Advanced Triple Negative Breast Cancer: The OLTRE Window of Opportunity Trial

Front Oncol. 2021; 11: 686776. Published online 2021 Jun 28. doi:

https://doi.org/10.3389/fonc.2021.686776

Alfredo Molteni, Alice Bruson, Carla Strina, Carlo Azzini, Daniele Generali, Davide Cerra, Elena Marasco, Elisa Zago, Fabiola Giudici, Francesco Schettini, Gareth H Williams, Giovanni Scambia, Giuseppina Barbieri, Giuseppina Ferrero, Ida Paris, Luciano Xumerle, Manuela Milani, Marco Loddo, Marco Ungari, Maria Chiara Lazzari, Maria Rosa Cappelletti, Marianna Sirico, Nicoletta Ziglioli, Ottavia Bernocchi, Sergio Aguggini, Silvia Paola Corona, Valeria Cervoni

SARS-CoV-2 testing and sequencing for international arrivals reveals significant cross border transmission of high risk variants into the United Kingdom

EClinical Medicine by the Lancet Published:July 14, 2021 DOI:

https://doi.org/10.1016/j.eclinm.2021.101021

Gareth H Williams, Alexander Llewelyn, Ruben Brandao, Kaiya Chowdhary,Keeda-Marie Hardisty, Marco Loddo (2021)

Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastoma

Published: March 25, 2022 DOI:

https://doi.org/10.1371/journal.pone.0245817

Gareth H Williams, Alexander Llewelyn, Robert Thatcher, Keeda-Marie Hardisty, Marco Loddo