Oncologica is a leading contract research organization specializing in small and large end-to-end bioinformatic CRO laboratory services. We offer bioanalytical clinical contract research to aid drug and targeted medicine innovation through our expertise in genetic cell-based assays, molecular biomarkers and immunogenicity services.
We work as a collaborative CRO partner to deliver integrated bioanalytical contract research solutions for your genomic sequencing needs. We excel in bioinformatics contract research where extensive sequencing capabilities and accurate detection of variants are required.
- Human genetics research partner
- Outsource genetic studies
- Bioanalytical pre-clinical contract research
- Drug manufacturing bioanalytical research
- UK based genetic CRO
Genomic Sequencing Services
Oncologica sequencing capabilities are suitable for:
- Rare disease studies
- Cancer exome analysis
- Complex disease genomics
- Translational research
RNA Sequencing Services
Our highly experienced bioinformatics team utilise lab sequencing and a leading genomic data library, for analysis and interpretation of:
- Gene expression
- Transcriptome analysis
- RNA sequencing services
Sequencing for the Microbiome
Our wide range sequencing capabilities allows our researchers to sequence all given genomic DNA in a complex sample. This provides valuable insights into community biodiversity and function. The sequencing data can be used for metagenomic assembly, function and gene resistance profiling.
Bacterial RNA Sequencing
Oncologica Sequencing provides bacterial RNA sequencing, which can identify and compare bacterial community in a sample by sequencing regions of the bacterial 16s rRNA gene.
- Access Oncologica’s large database of genomic data
- Undertake bioinformatic analysis for taxonomy assignment
Exploring the interaction between siRNA and the SMoC biomolecule transporters: implications for small molecule-mediated delivery of siRNA
Chem Biol Drug Des. 2012 Jan;79(1):9-21.
Gooding M, Tudzarova S, Worthington RJ, Kingsbury SR, Rebstock AS, Dube H, Simone MI, Visintin C, Lagos D, Quesada JM, Laman H, Boshoff C, Williams GH, Stoeber K, Selwood DL.
Molecular architecture of the DNA replication origin activation checkpoint
EMBO J. 2010 Oct 6;29(19):3381-94.
Tudzarova S, Trotter MW, Wollenschlaeger A, Mulvey C, Godovac-Zimmermann J, Williams GH, Stoeber K.
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle
Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5278-83.
Tudzarova S, Colombo SL, Stoeber K, Carcamo S, Williams GH, Moncada S.
Targeting DNA replication before it starts: Cdc7 as a therapeutic target in p53-mutant breast cancers
Am J Pathol. 2010 Oct;177(4):2034-45.
Rodriguez-Acebes S, Proctor I, Loddo M, Wollenschlaeger A, Rashid M, Falzon M, Prevost AT, Sainsbury R, Stoeber K, Williams GH.
Diagnosis of prostate cancer by detection of minichromosome maintenance 5 protein in urine sediments
Br J Cancer. 2010 Aug 24;103(5):701-7.
Dudderidge TJ, Kelly JD, Wollenschlaeger A, Okoturo O, Prevost T, Robson W, Leung HY, Williams GH, Stoeber K.