Oncofocus Tumour Genetic Analysis
The Oncofocus test is covered by all leading health insurers
- Personalised genetic profile for early and advanced stage disease
- For all solid tumour types (except leukaemia)
- Uses the histology/biopsy tissue sample from initial diagnosis
- Results for patients and oncologists is available 15 working days from sample receipt
- Free standard worldwide sample shipment and hospital return
- Phone, chat and email support
The Oncofocus® precision oncology test generates a personalised genetic profile to help clinicians and oncologists identify the right targeted drug to increase treatment success.
It works by sequencing the DNA and RNA of an individual’s tumour to generate a personalised genetic profile (blueprint) and incorporates the most up to date genomic information linked to targeted therapies.
Oncofocus® targets 505 genes with actionable genetic mutations linked to 700 anti-cancer targeted therapies or treatments in clinical trials.
What are targeted therapies
Targeted therapies are drugs that kill cancer cells but do not affect normal cells compared with chemotherapy which kills cancer and normal cells. Targeted cancer therapies are the form of personalised medicine that uses information about a person’s DNA profile to help treat your cancer.
Targeted therapy vs chemotherapy
Targeted therapies are much more effective than chemotherapy because they are designed to
- Specifically hit the target mutations present only in cancer cells
- Normal cells are unaffected by the treatment
- Toxic side effects are minimised
Every persons cancer is unique
Every person’s tumour is unique because each person acquires different cancer DNA mutations during development of their disease. Today there are 700 drugs which target each of these DNA mutation types.
The Oncofocus Test can be used for all Cancers, including:
Oncofocus cancer test can help identify optimal treatment options following initial diagnosis. This helps avoid costs and side effects from potentially ineffective drugs.
Widespread Advanced Cancers
The Oncofocus cancer test can identify a broad range of additional therapeutic options for patients who have exhausted conventional treatments such as chemotherapy.
Rare or Unknown Cancers
Treatment decisions for rare unknown cancers are challenging for your oncologist because of a lack of established therapeutic protocols. The Oncofocus test is ideally suited for the analysis of such cases enabling the precise matching of these tumours to the most appropriate therapy.
Difficult to Treat Cancers
The Oncofocus test can be used for re-testing to identify new genetic changes acquired following relapse and allow the new mutations to be directly matched to a new set of targeted therapies.
Our DNA genetic cancer test can help guide your doctors on whether you are able to join a clinical trial. The genetic data from a clinical trial may be used in your individual care, improving the health services you and others receive and further research.
For all the information on our Oncofocus test, download our brochure.
Is the Oncofocus test applicable to my cancer type?
Oncofocus is applicable to all tumour types except leukaemia.
If I have cancer, why have a genetic cancer test?
For individuals diagnosed with cancer, genetic testing can help your doctors determine the best type of targeted therapies and avoid more toxic chemotherapy. Genetic cancer testing can give your relatives information about their cancer risk
Are Oncologica’s genetic cancer tests the same as the ones offered by the NHS?
Yes, our genetic cancer tests use the same technology as those offered through the NHS. However the NHS is under significant strain due to the pandemic and its effect on cancer services. Cancer survival rates in the UK are set to reach their lowest in 15 years, with 3 million people missing routine cancer screening appointments during the pandemic – a service which normally diagnoses around 400 cancers a week. The disruption to cancer services has resulted in a backlog in cancer screening of 3-6 months of delays to treatment.
Concerns over delays means Oncologica’s cancer tumour genetic profiling can help provide a genetic tumour blueprint for you and your doctors to aid medicine treatment choices.
How do I order the Oncofocus test?
Ordering can be requested by patients via our website or by completing our test request form and patient consent forms which are submitted to our Oncofocus Clinical Admin Team after a preliminary initial discussion appointment request with them.
What does the Oncofocus test include?
Oncofocus and Immunofocus tests include the courier costs, to ensure the samples are delivered safely and quickly, a telephone consultation with our Doctor once you have your results, and ongoing supplementary reports as requested by patients.
How long does it take to get Oncofocus test results?
Once a patients sample has been booked inside our lab, the test process takes up to 15 working days. This excludes weekends and bank holidays.
A friend recommends you as her mother is surviving advanced lung cancer on your treatment plus NHS drugs, so I hope we can do the same. She is convinced you have extended her mother’s life.
Oncologica®Ltd is a great company who look more in depth into cancerous tumours and identify what treatments will work with your unique tumour type. They have been amazing and anyone who is going through cancer treatment, you need to look at this company.
My wife is now on a targeted therapy programme rather than chemo or radiation. She is doing great, you helped save her life, thanks
Having exhausted standard therapy for my stage 4 bowel cancer, Oncologica® identified a targeted immunotherapy, which would work on my rare genotype. After just 4 weeks of treatment, I have gone from being bedbound to swimming, walking and fully enjoying all that life has to offer again. I am truely grateful.
• Several relatives with the same or linked types of cancer
• Relatives diagnosed at particularly young ages (before 50)
• Several affected generations
• Individuals who have been diagnosed with multiple cancers
Cancers which can be linked in some families are Breast, ovarian, prostate, pancreatic, Bowel, womb and stomach cancers.
DNA (Deoxyribonucleic acid) contains the genetic instructions in all living things. DNA is made up of two strands that form a double helix. A DNA strand has four different bases arranged in different orders. These bases are T (thymine), A (adenine), C (cytosine), and G (guanine). DNA is “read” by the order of the bases, Ts, Cs, Gs, and As. The specific order, or sequence, of these bases determines the exact information carried in each gene (e.g., instructions for making a specific protein).
Oncology is the study of cancer. An Oncologist is a doctor who treats cancer and provides medical care for a person diagnosed with cancer.
Targeted therapy is Treatment that targets specific genes, proteins, or other molecules that contribute to cancer growth and survival.
Mutations All cancers begin when one or more genes in a cell mutate. A mutation is a change. It creates an abnormal protein. Or it may prevent a protein’s formation. Mutations happen often and may be beneficial, harmful, or neutral. Typically, the body corrects most mutations. A single mutation will likely not cause cancer. Usually, cancer occurs from multiple mutations over a lifetime. That is why cancer occurs more often in older people.
Check the status of your Oncofocus test through our Dashboard.
The Oncofocus® cancer test allows your clinician to accurately identify the best treatment for your cancer.
Oncofocus® may be requested by your hospital, doctor or oncologist. If your doctor is not aware of this test option, our patient consultants can guide you and suggest the best option to present Oncofocus® to your doctor to get an Oncofocus® test in your country.
As a clinician, you will have a powerful tool to optimise therapy choices and improve patient outcomes.
As a clinician you can register and request a test today. If you need more information or have any questions about the Oncofocus® cancer test you can also request a consultation with our Oncologica® Support team.